Chemoembolization & Radioembolization
Chemoembolization and radioembolization are liver-directed cancer therapies that deliver high-dose treatment directly to tumors while minimizing exposure to healthy tissue. These procedures are performed by interventional radiologists using advanced imaging guidance.
Symptom Onset & Initial Evaluation
Patients are typically referred for chemoembolization or radioembolization after imaging or clinical evaluation shows liver tumors that are not amenable to surgery. These therapies are most often considered for individuals with:
- Primary liver cancer that cannot be safely removed
- Liver-dominant metastatic disease where tumors are confined mainly to the liver
- Preserved liver function but limited surgical or ablative treatment options
During the initial evaluation at The Medical Group of New Jersey, providers review cancer type, tumor burden, liver function, prior treatments, and overall health to determine whether liver-directed therapy is appropriate.
Diagnosis
Careful diagnostic planning is essential to ensure both safety and effectiveness. Evaluation typically includes:
- Contrast-enhanced CT or MRI to define tumor size, number, and vascular supply
- Blood tests to assess liver function and overall treatment tolerance
- Angiographic mapping studies to evaluate liver blood flow and plan catheter-based delivery
These assessments help tailor treatment to the individual patient while minimizing risk to healthy liver tissue.
Treatment Guidance & Management
During treatment, interventional radiologists use imaging guidance to deliver therapy precisely where it is needed. This approach involves:
- Catheter-directed delivery of chemotherapy or radioactive particles into the arteries feeding the tumor
- Concentrated tumor treatment with reduced exposure to the rest of the body
Most procedures are performed with conscious sedation or anesthesia and do not require open surgery.
Ongoing Management & Monitoring
Following treatment, patients are followed closely to assess response and recovery. Follow-up care typically includes:
- Scheduled imaging to evaluate tumor response and stability
- Ongoing monitoring of liver function and symptoms
- Close collaboration with medical oncology and hepatology to guide further cancer care
This coordinated, multidisciplinary approach ensures that treatment decisions remain aligned with each patient’s overall cancer plan and long-term goals.